Osteoarthritis could be delayed by removing SnCs from joints

ISLAMABAD: The selective removal of Senescent cells (SnCs) from joints could reduce the development of post-traumatic osteoarthritis and allow new cartilage to grow and repair joints.

Health News reported that the findings suggest that SnCs accumulate with age in many vertebrate tissues and are present at sites of age-related pathology.

Although SnC cells play an essential role in wound healing and injury repair, they often are not cleared from knee and cartilage tissue after an injury, thereby contributing to the development of osteoarthritis.

They may also promote cancer incidence in tissues, the researchers said.

The study may provide new insights into therapies targetingSnCs for the treatment of trauma and age-related degenerative joint disease, said Chaekyu Kim from the Ulsan National Institute of Science and Technology (UNIST) in South Korea.

The study also presented a novel pharmacologic candidate that alleviates age-related osteoarthritis by selectively destroying SnCs.