Christina Applegate gets real about living with multiple sclerosis

Christina Applegate has an update about her ongoing struggle with multiple sclerosis.

The actress, 53, opened up about her cancer battle on May 5 during an appearance on Conan O’Brien Needs a Friend.

"If people saw what my life was like on the daily, they wouldn't they wouldn't be able to do it. Because I can sometimes not do it. It's really, really hard," Applegate shared on the podcast.

"I don't really leave the house anymore," Applegate told O’Brien.

She shared she’s often asked, "'How did you get it?' … Meaning, I must have done something wrong in my life to have this disease. I did it to myself."

The Married… with Children alum, who got her multiple sclerosis diagnosis in 2021, recalled how her earlier breast cancer diagnosis in 2008 also drew similar concerns.

"It's, like, I had breast cancer as well, so, ‘Oh, you must have done something,’" she said, referencing her 2008 diagnosis. "That stigma is — I'm used to it now, but it was for a while, like, was so hard to swallow because why the f*** would you think that I would do something to have this?"