Thursday Dec 01, 2022
With over 450 million people suffering from diabetes, a medical breakthrough might be close as an Israeli company claims to be on the edge of finding the cure to the illness.
The company's medical director said that the scientists in the team are looking to find a cure by developing a fake pancreas made out of real human cells.
Kadimastem, the firm committed to the cause, is currently in the pre-clinical phase in an Israeli town, Ness Ziona. While the clinical trials have not started yet, the results look very promising.
"We have reached successful pre-clinical results of our cell therapy treatment for insulin-dependent diabetes," the company revealed in an official statement.
"Kadimastem is focused on the generation and manufacturing of pancreatic insulin-secreting islets (IsletRx) from embryonic stem cells for the treatment of insulin-dependent diabetes such as Type 1 Diabetes," the health tech firm explained, adding that the will be holding human trials very soon.
If the experiment turns out to be successful in all its phases, it would result in a revolutionary invention, providing a cure to millions of people across the globe. Not only will it offer a cure but also might help those unable to afford treatments, considering the prices of insulting have been skyrocketing.
The results of the study conducted by the company showed that IsletRx was safely delivered. They jduged the efficacy by observing the maintained "normalised blood sugar level in treated immunocompetent diabetic mice throughout the duration of the preclinical study (three months)."
The company reported that no treatment-related complications occurred. "In comparison, a control group of non-treated diabetic mice presented severe hyperglycemia, leading to the death of the non-treated mice within 40 days," the report read.
The company is not only focusing on finding a cure for diabetes. Their aim is "to develop innovative regenerative therapies for incurable diseases" in general.
Back in August, the firm was awarded a patent for an ALS treatment. Soon it received a third patent for diabetes.
With reports of diabetes medicines having carcinogens in them, a cure like the one Kadimastem is working on could remove any extra risks. The work on finding the cure for diabetes brings hope to many patients.
Not long ago, a team of researchers at the University of British Columbia in Canada announced they have developed an oral drug that can act as an alternative to insulin injections.
The oral tablet can replace needles and deliver the entire dosage to a diabetic patient's liver. Previous attempts at creating such a medication failed as the drug would mostly end up in the stomach instead of being absorbed in the liver.
Many diabetic patients have to use needles multiple times a day to manage their illness and provide insulin to the body.